Trial intelligence / Profile preview

Phase III comparison of ranibizumab, aflibercept, and bevacizumab for macular oedema due to central retinal vein occlusion

2014-000272-26Phase 3Completed

Sponsor
Moorfields Eye Hospital
Start
Jun 2014
Modality
Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 3, randomised, double-blind trial in central retinal vein occlusion (CRVO) comparing Lucentis arm, Eylea arm and Avastin arm (3 arms). Primary endpoint: Change in mean best corrected visual acuity from baseline to 100 weeks. Started Jun 2014; status: completed.

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Drugs

ranibizumabafliberceptbevacizumab
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Conditions

central retinal vein occlusion (CRVO)

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