Trial intelligence / Profile preview

Ranibizumab versus aflibercept for systemic VEGF dynamics in neovascular age-related macular degeneration

2014-001182-27Phase 4Terminated

Sponsor
Novartis
Start
Jun 2014
Modality
Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics, Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes, Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 4, randomised, single-blind trial in exudative macular degeneration comparing Monthly ranibizumab with Monthly aflibercept (2 arms). Primary endpoint: Systemic VEGF-A protein levels from baseline to week 12. Started Jun 2014; status: terminated.

02

Drugs

ranibizumabaflibercept
03

Conditions

exudative macular degeneration

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