Trial intelligence / Profile preview

AALL1131 high-risk B-ALL trial testing clofarabine in the very high-risk stratum

2014-001866-90Phase 3Terminated

Sponsor
Children's Oncology Group
Start
May 2014
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of clofarabine and methotrexate in B cell acute lymphoblastic leukemia (B-ALL) (3 arms), sponsored by Children's Oncology Group. Primary endpoint: 5-year disease-free survival. Started May 2014; status: terminated.

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Drugs

clofarabinemethotrexate
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Conditions

B cell acute lymphoblastic leukemia (B-ALL)

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