Trial intelligence / Profile preview

Radium-223 plus exemestane and everolimus versus placebo plus exemestane and everolimus in hormone receptor-positive HER2-negative metastatic breast cancer with bone metastases

2014-002114-23Phase 2Completed

Sponsor
Bayer
Start
Sep 2014
Modality
Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Alpha Emitters → Radiopharmaceuticals
Countries
1
01

Overview

Phase 2, randomised, double-blind trial in breast cancer comparing Radium-223 + exemestane + everolimus with Placebo + exemestane + everolimus (2 arms). Primary endpoint: Symptomatic skeletal event-free survival. Started Sep 2014; status: completed.

02

Drugs

radium-223 dichlorideexemestaneeverolimus
03

Conditions

breast cancer

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