Trial intelligence / Profile preview

PF-03084014 monotherapy in advanced triple-negative breast cancer with or without Notch receptor genomic alterations

2014-002286-30Phase 2Terminated

Sponsor
Pfizer
Start
Oct 2014
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, open-label trial of nirogacestat in triple-negative breast cancer (TNBC) (2 cohorts), sponsored by Pfizer. Primary endpoint: Objective response in Notch alteration-positive metastatic triple-negative breast cancer. Started Oct 2014; status: terminated.

02

Drugs

nirogacestat
03

Conditions

triple-negative breast cancer (TNBC)

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