Trial intelligence / Profile preview

MK-5172A versus sofosbuvir + peginterferon/ribavirin in chronic hepatitis C

2014-003836-38Phase 3Completed

Sponsor
Merck & Co.
Start
Nov 2014
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, open-label trial of elbasvir + grazoprevir, sofosbuvir, peginterferon alfa-2b and ribavirin in chronic hepatitis C (CHC) (2 arms), sponsored by Merck & Co. Primary endpoint: SVR12 rate. Started Nov 2014; status: completed.

02

Drugs

elbasvir + grazoprevirsofosbuvirpeginterferon alfa-2bribavirin
03

Conditions

chronic hepatitis C (CHC)

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