Trial intelligence / Profile preview

Phase IV study of TDF/FTC with raltegravir, dolutegravir, or elvitegravir/cobicistat on renal tubular function in antiretroviral-naive HIV-1 patients

2014-004578-40Phase 4Completed

Sponsor
St Stephen's AIDS Trust
Start
Jan 2016
Modality
Small Molecules
Countries
1
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Overview

Phase 4, open-label trial of emtricitabine + tenofovir disoproxil, raltegravir, dolutegravir and emtricitabine + elvitegravir + cobicistat + tenofovir disoproxil in human immunodeficiency virus infection (HIV) (3 arms), sponsored by St Stephen's AIDS Trust. Primary endpoint: Change in retinol-binding protein/creatinine ratio at 24 weeks. Started Jan 2016; status: completed.

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Drugs

emtricitabine + tenofovir disoproxilraltegravirdolutegraviremtricitabine + elvitegravir + cobicistat + tenofovir disoproxil
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Conditions

human immunodeficiency virus infection (HIV)

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