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Hydroxyurea pharmacokinetics by renal function in adults with sickle cell disease
2014-005033-31Phase 4Completed
- Sponsor
- ADDMEDICA
- Start
- Feb 2015
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 4, open-label trial of hydroxyurea in sickle cell disease (SCD) (3 arms), sponsored by ADDMEDICA. Primary endpoint: Comparison of pharmacokinetic parameters across renal function groups. Started Feb 2015; status: completed.
02
Drugs
hydroxyurea
03
Conditions
sickle cell disease (SCD)
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