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Prophylactic treatment of osteoradionecrosis with pentoxifylline and alpha-tocopherol (PENTO)
2015-000887-32Phase 2Completed
- Sponsor
- Region Västra Götaland
- Start
- May 2015
- Modality
- Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 2, single-arm trial of pentoxifylline and tocopherol in osteoradionecrosis of the jaws (ORN) and osteonecrosis, sponsored by Region Västra Götaland. Primary endpoint: Tissue and bone healing (primary). Started May 2015; status: completed.
02
Drugs
pentoxifyllinetocopherol
03
Conditions
osteoradionecrosis of the jaws (ORN)osteonecrosis
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