Trial intelligence / Profile preview

Phase 2 randomized single-blind study of imetelstat dose levels in relapsed/refractory myelofibrosis after JAK inhibitor treatment

2015-000946-41Phase 2Completed

Sponsor
Geron Corporation
Start
Apr 2015
Modality
Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
01

Overview

Phase 2, randomised, single-blind trial of imetelstat in myelofibrosis (MF) (2 arms), sponsored by Geron Corporation. Primary endpoint: Spleen response rate at Week 24. Started Apr 2015; status: completed.

02

Drugs

imetelstat
03

Conditions

myelofibrosis (MF)

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