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Phase II Study of Durvalumab Alone or with Tremelimumab in Metastatic Pancreatic Ductal Adenocarcinoma

2015-002001-11Phase 2Completed

Sponsor
AstraZeneca
Start
Sep 2015
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, randomised, open-label trial in pancreatic adenocarcinoma (PDAC) comparing Durvalumab monotherapy, Durvalumab + tremelimumab and Standard-of-care chemotherapy (3 arms). Primary endpoint: Objective response rate. Started Sep 2015; status: completed.

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Drugs

durvalumabtremelimumab
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Conditions

pancreatic adenocarcinoma (PDAC)

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