Trial intelligence / Profile preview

mFOLFOX6 vs. mFOLFOX6 + aflibercept as neoadjuvant treatment in MRI-defined T3 rectal cancer

2015-002773-38Phase 2Completed

Sponsor
AIO-Studien
Start
Aug 2016
Modality
Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes, Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 2, randomised trial of aflibercept in rectal cancer, rectosigmoid cancer and colorectal cancer (CRC) (2 arms), sponsored by AIO-Studien. Primary endpoint: Pathologic complete response rate. Started Aug 2016; status: completed.

02

Drugs

aflibercept
03

Conditions

rectal cancerrectosigmoid cancercolorectal cancer (CRC)

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