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PARABLE: LCZ696 (ARNI) vs valsartan in patients with elevated natriuretic peptides
2015-002928-53Phase 2Completed
- Sponsor
- The Heartbeat Trust
- Start
- Sep 2015
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Phase 2, randomised trial of sacubitril + valsartan in diastolic dysfunction, heart failure (HF), hypertension (HTN) and 2 more (2 arms), sponsored by The Heartbeat Trust. Primary endpoint: Change in left atrial volume index (LAVI) by cMRI at 18 months. Started Sep 2015; status: completed.
02
Drugs
sacubitril + valsartan
03
Conditions
diastolic dysfunctionheart failure (HF)hypertension (HTN)type 2 diabetes mellitus (T2DM)cardiac morbidity
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