Adjunctive minocycline for treatment-resistant depression with increased inflammation

Phase 4, randomised trial in treatment-resistant depression (TRD) and major depressive disorder (MDD) comparing Minocycline adjunctive arm with Placebo adjunctive arm (2 arms). Primary endpoints: Hamilton Depression Rating Scale total score change from baseline to Week 4 and Hamilton Depression Rating Scale response rate at Week 4. Started Dec 2015; status: completed.