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Total thyroidectomy vs thionamides in moderate-to-severe Graves' ophthalmopathy
2015-003515-38Phase 3Terminated
- Sponsor
- Medical University of Vienna
- Start
- Sep 2015
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
- Countries
- 1
01
Overview
Phase 3, randomised, open-label trial of methimazole, propylthiouracil and methylprednisolone in Graves' disease, Graves' ophthalmopathy (TED) and hyperthyroidism (2 arms), sponsored by Medical University of Vienna. Primary endpoints: Clinical Activity Score and NOSPECS parameters at 6 months, Clinical Activity Score and NOSPECS parameters at 12 months and 2 more. Started Sep 2015; status: terminated.
02
Drugs
methimazolepropylthiouracilmethylprednisolone
03
Conditions
Graves' diseaseGraves' ophthalmopathy (TED)hyperthyroidism
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