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Prospective pilot trial of multimodal targeted therapy (RIST protocol) in relapsed or refractory high-grade pineoblastoma

2015-004304-27Phase 2Completed

Sponsor
Universitätsklinikum Regensburg
Start
Mar 2016
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, single-arm trial of dasatinib, temozolomide, sirolimus and irinotecan in pineoblastoma (PB), sponsored by Universitätsklinikum Regensburg. Primary endpoint: Progression-free survival. Started Mar 2016; status: completed.

02

Drugs

dasatinibtemozolomidesirolimusirinotecan
03

Conditions

pineoblastoma (PB)

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