Trial intelligence / Profile preview

Open-label Study of Neratinib with Intensive Loperamide Prophylaxis in Early Stage HER2+ Breast Cancer

2015-004374-15Phase 2Completed

Sponsor
Puma Biotechnology, Inc.
Start
Feb 2018
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of neratinib in breast cancer, sponsored by Puma Biotechnology, Inc. Primary endpoint: Incidence of Grade 3 diarrhea. Started Feb 2018; status: completed.

02

Drugs

neratinib
03

Conditions

breast cancer

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