Trial intelligence / Profile preview

Durvalumab with R-CHOP or lenalidomide plus R-CHOP in previously untreated high-risk diffuse large B-cell lymphoma

2015-005173-20Phase 2Completed

Sponsor
Celgene Corporation
Start
Oct 2016
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label trial of durvalumab, lenalidomide, rituximab, cyclophosphamide, doxorubicin and 2 more in diffuse large B-cell lymphoma (DLBCL) (2 arms), sponsored by Celgene Corporation. Primary endpoint: Complete response rate at end of induction therapy. Started Oct 2016; status: completed.

02

Drugs

durvalumablenalidomiderituximabcyclophosphamidedoxorubicin
03

Conditions

diffuse large B-cell lymphoma (DLBCL)

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