Trial intelligence / Profile preview

Pembrolizumab with or without platinum-based chemotherapy versus chemotherapy for advanced or metastatic urothelial carcinoma

2015-005731-41Phase 3Completed

Sponsor
Merck & Co.
Start
Aug 2016
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of pembrolizumab, gemcitabine, cisplatin and carboplatin in transitional cell carcinoma (TCC) (3 arms), sponsored by Merck & Co. Primary endpoints: Progression-free survival and Overall survival. Started Aug 2016; status: completed.

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Drugs

pembrolizumabgemcitabinecisplatincarboplatin
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Conditions

transitional cell carcinoma (TCC)

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