Trial intelligence / Profile preview

AML-ViVA phase II trial of low-dose azacitidine + tretinoin + pioglitazone versus standard-dose azacitidine in older patients with refractory AML

2016-000421-39Phase 2Terminated

Sponsor
Universitätsklinikum Regensburg
Start
Nov 2016
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, randomised trial in acute myeloid leukemia (AML) comparing Low-dose azacitidine + tretinoin + pioglitazone with Standard-dose azacitidine (2 arms). Primary endpoint: Overall survival. Started Nov 2016; status: terminated.

02

Drugs

azacitidinetretinoinpioglitazone
03

Conditions

acute myeloid leukemia (AML)

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