Trial intelligence / Profile preview

Panitumumab + mFOLFOX-6 induction therapy before surgery in quadruple wild-type intermediate-risk rectal cancer

2016-002333-29Phase 2Terminated

Sponsor
GEMCAD
Start
Feb 2017
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of panitumumab, fluorouracil, folinic acid and oxaliplatin in rectal adenocarcinoma and colorectal cancer (CRC), sponsored by GEMCAD. Primary endpoint: Pathologic complete response. Started Feb 2017; status: terminated.

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Drugs

panitumumabfluorouracilfolinic acidoxaliplatin
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Conditions

rectal adenocarcinomacolorectal cancer (CRC)

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