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Lorlatinib versus crizotinib in first-line advanced ALK-positive non-small cell lung cancer
2016-003315-35Phase 3Active
- Sponsor
- Pfizer
- Start
- Apr 2017
- Modality
- Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 3, randomised, open-label trial in non-small cell lung cancer (NSCLC) comparing Lorlatinib monotherapy with Crizotinib monotherapy (2 arms). Primary endpoint: Progression-free survival. Started Apr 2017; status: active.
02
Drugs
lorlatinibcrizotinib
03
Conditions
non-small cell lung cancer (NSCLC)
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