Trial intelligence / Profile preview

TAHOE: rovalpituzumab tesirine versus topotecan in DLL3-high relapsed small cell lung cancer

2016-003726-17Phase 3Completed

Sponsor
AbbVie Inc.
Start
May 2017
Modality
Small Molecules, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 3, randomised, open-label trial in small cell lung cancer (SCLC) comparing Rovalpituzumab tesirine with Topotecan (2 arms). Primary endpoint: Overall survival. Started May 2017; status: completed.

02

Drugs

rovalpituzumab tesirinetopotecan
03

Conditions

small cell lung cancer (SCLC)

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