Proof-of-concept multiple intra-articular LNA043 injections for cartilage regeneration in knee articular cartilage lesions

Phase 2, randomised, double-blind trial in chondral knee defect, knee osteoarthritis (OA) and Traumatic cartilage degeneration comparing LNA043 intra-articular injections with Placebo intra-articular injections (2 arms). Primary endpoint: Articular cartilage bilayer collagen organisation evaluated with T2. Started Mar 2017; status: completed.