Trial intelligence / Profile preview

Cobimetinib plus atezolizumab vs pembrolizumab in untreated BRAF V600 wild-type advanced melanoma

2016-004387-18Phase 3Completed

Sponsor
Roche
Start
Sep 2017
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 3, randomised, open-label trial in melanoma and cutaneous malignancy comparing Cobimetinib + atezolizumab with Pembrolizumab (2 arms). Primary endpoint: Progression-free survival by independent review committee. Started Sep 2017; status: completed.

02

Drugs

cobimetinibatezolizumabpembrolizumab
03

Conditions

melanomacutaneous malignancy

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