Trial intelligence / Profile preview

YAPPETIZER study of neoadjuvant chemotherapy with or without zoledronic acid and atorvastatin in triple-negative breast cancer

2016-005112-17Phase 2Completed

Sponsor
Mario Negri Institute for Pharmacological Research
Start
Jun 2021
Modality
Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of zoledronic acid and atorvastatin in triple-negative breast cancer (TNBC) (2 arms), sponsored by Mario Negri Institute for Pharmacological Research. Primary endpoints: Relative reduction of YAP IHC expression and Relative reduction of TAZ IHC expression. Started Jun 2021; status: completed.

02

Drugs

zoledronic acidatorvastatin
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Conditions

triple-negative breast cancer (TNBC)

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