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Dose-escalation study of GSK2586881 in pulmonary arterial hypertension

2017-000212-41Phase 2Completed

Sponsor
GSK
Start
Jun 2017
Modality
Replacement Enzymes → Therapeutic Enzymes → Recombinant Proteins and Enzymes, Peptides
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of alunacedase alfa in pulmonary arterial hypertension (PAH), sponsored by GSK. Primary endpoints: Change from baseline in pulmonary vascular resistance (PVR), Change from baseline in cardiac output (CO) and 1 more. Started Jun 2017; status: completed.

02

Drugs

alunacedase alfa
03

Conditions

pulmonary arterial hypertension (PAH)

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