Trial intelligence / Profile preview

KEYNOTE-590 pembrolizumab plus cisplatin and fluorouracil in advanced or metastatic esophageal carcinoma

2017-000958-19Phase 3Completed

Sponsor
Merck & Co.
Start
Apr 2017
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 3, randomised, double-blind trial in esophageal cancer and gastroesophageal junction adenocarcinoma comparing Pembrolizumab + cisplatin + fluorouracil with Placebo + cisplatin + fluorouracil (2 arms). Primary endpoints: Progression-free survival and Overall survival. Started Apr 2017; status: completed.

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Drugs

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Conditions

esophageal cancergastroesophageal junction adenocarcinoma

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