Trial intelligence / Profile preview

Domatinostat plus avelumab in previously treated mismatch repair proficient oesophagogastric and colorectal cancers

2017-001770-42Phase 2Unknown

Sponsor
Royal Marsden NHS Foundation Trust
Start
Mar 2018
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of Domatinostat and avelumab in gastroesophageal junction adenocarcinoma and colorectal cancer (CRC), sponsored by Royal Marsden NHS Foundation Trust. Primary endpoints: Efficacy of domatinostat added to avelumab and Radiological response. Status: unknown.

02

Drugs

Domatinostatavelumab
03

Conditions

gastroesophageal junction adenocarcinomacolorectal cancer (CRC)

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