Trial intelligence / Profile preview

Zolbetuximab plus mFOLFOX6 versus placebo plus mFOLFOX6 in first-line CLDN18.2-positive HER2-negative advanced gastric or gastroesophageal junction adenocarcinoma

2017-002567-17Phase 3Active

Sponsor
Astellas Pharma
Start
May 2018
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, double-blind trial in gastric adenocarcinoma and gastroesophageal junction adenocarcinoma comparing Zolbetuximab plus mFOLFOX6 with Placebo plus mFOLFOX6 (2 arms). Primary endpoint: Progression-free survival. Started May 2018; status: active.

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Drugs

zolbetuximab
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Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinoma

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