Trial intelligence / Profile preview

Vemurafenib + cobimetinib beyond focal progression versus second-line therapy in BRAF V600-mutant metastatic melanoma

2017-003038-98Phase 2Completed

Sponsor
Intergruppo Melanoma Italiano
Start
Jun 2021
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label trial of vemurafenib, cobimetinib, nivolumab and pembrolizumab in melanoma (2 arms), sponsored by Intergruppo Melanoma Italiano. Primary endpoint: Overall survival in patients with focal progression. Started Jun 2021; status: completed.

02

Drugs

vemurafenibcobimetinibnivolumabpembrolizumab
03

Conditions

melanoma

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