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Post-operative radiotherapy plus nivolumab + ipilimumab versus radiotherapy plus capecitabine in triple-negative breast cancer with residual disease

2017-003151-34Phase 2Completed

Sponsor
Centre Léon Bérard
Start
Nov 2018
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial in triple-negative breast cancer (TNBC) comparing Radiotherapy + nivolumab + ipilimumab with Radiotherapy + capecitabine (2 arms). Primary endpoint: Disease-free survival. Started Nov 2018; status: completed.

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Drugs

nivolumabipilimumabcapecitabine
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Conditions

triple-negative breast cancer (TNBC)

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