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Phase 2 Double-Blind Randomized Study of ISIS 484137 in Hepatic Steatosis in Adults with Type 2 Diabetes

2017-003197-13Phase 2Completed

Sponsor
Ionis Pharmaceuticals
Start
Oct 2017
Modality
Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Single-strand DNA → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Modified DNA Oligonucleotides → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
01

Overview

Phase 2, randomised, double-blind trial in steatosis and type 2 diabetes mellitus (T2DM) comparing ISIS 484137 with Placebo (2 arms). Primary endpoint: Safety endpoints. Started Oct 2017; status: completed.

02

Drugs

IONIS-DGAT2Rx
03

Conditions

steatosistype 2 diabetes mellitus (T2DM)

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