Trial intelligence / Profile preview

KEYNOTE-789 in TKI-resistant EGFR-mutated metastatic non-squamous NSCLC

2017-004188-11Phase 3Completed

Sponsor
Merck & Co.
Start
Mar 2018
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 3, randomised, double-blind trial in non-small cell lung cancer (NSCLC), Non-small cell lung cancer (NS-NSCLC) and EGFR-mutated non-small cell lung cancer comparing Pembrolizumab + pemetrexed + platinum chemotherapy with Placebo + pemetrexed + platinum chemotherapy (2 arms). Primary endpoint: Progression-free survival. Started Mar 2018; status: completed.

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Drugs

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Conditions

non-small cell lung cancer (NSCLC)Non-small cell lung cancer (NS-NSCLC)EGFR-mutated non-small cell lung cancer

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