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Phase II randomized study of nal-irinotecan + 5-fluorouracil/leucovorin, gemcitabine + nab-paclitaxel, or sequential alternating treatment in metastatic pancreatic cancer

2017-004309-41Phase 2Active

Sponsor
Fédération Francophone de Cancérologie Digestive
Start
Apr 2018
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Liposomes → Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Countries
1
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Overview

Phase 2, randomised, open-label trial of irinotecan liposomal, fluorouracil, folinic acid, gemcitabine and paclitaxel in pancreatic adenocarcinoma (PDAC) and pancreatic cancer (PDAC) (3 arms), sponsored by Fédération Francophone de Cancérologie Digestive. Primary endpoint: Rate of patients alive without progression at 6 months. Started Apr 2018; status: active.

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Drugs

irinotecan liposomalfluorouracilfolinic acidgemcitabinepaclitaxel
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Conditions

pancreatic adenocarcinoma (PDAC)pancreatic cancer (PDAC)

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