Trial intelligence / Profile preview

Avelumab plus chemotherapy followed by avelumab + talazoparib maintenance versus chemotherapy + bevacizumab in first-line advanced ovarian cancer

2017-004456-30Phase 3Terminated

Sponsor
Pfizer
Start
Jun 2018
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 3, randomised, open-label trial of avelumab, talazoparib and bevacizumab in ovarian cancer, fallopian tube cancer (PFTC) and primary peritoneal cancer (PPC) (2 arms), sponsored by Pfizer. Primary endpoint: Progression-Free Survival. Started Jun 2018; status: terminated.

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Drugs

avelumabtalazoparibbevacizumab
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Conditions

ovarian cancerfallopian tube cancer (PFTC)primary peritoneal cancer (PPC)

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