Trial intelligence / Profile preview

COCA study of esomeprazole and Coca-Cola effects on capecitabine absorption

2017-004465-27Phase 4Completed

Sponsor
Erasmus MC Cancer Institute
Start
Dec 2017
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
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Overview

Phase 4, open-label, single-arm trial of capecitabine and esomeprazole in colorectal cancer (CRC) and Nonhematologic neoplasms, sponsored by Erasmus MC Cancer Institute. Primary endpoint: Area under the plasma concentration-time curve of capecitabine. Started Dec 2017; status: completed.

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Drugs

capecitabineesomeprazole
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Conditions

colorectal cancer (CRC)Nonhematologic neoplasms

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