Trial intelligence / Profile preview

KEYNOTE-756: Pembrolizumab vs placebo with neoadjuvant chemotherapy and adjuvant endocrine therapy in high-risk early-stage ER+/HER2– breast cancer

2017-004869-27Phase 3Active

Sponsor
Merck & Co.
Start
Jun 2018
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 3, randomised, double-blind trial in breast cancer comparing Pembrolizumab arm with Placebo arm (2 arms). Primary endpoint: Pathological Complete Response Rate (ypT0/Tis ypN0). Started Jun 2018; status: active.

02

Drugs

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Conditions

breast cancer

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