Trial intelligence / Profile preview

Selenium and cholecalciferol added to methimazole in Graves' hyperthyroidism

2017-005050-11Phase 4Completed

Sponsor
ASST Sette Laghi
Start
Sep 2021
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, randomised, open-label trial in Graves' disease and hyperthyroidism comparing Methimazole standard therapy with Methimazole plus selenium and cholecalciferol (2 arms). Primary endpoint: Biochemical and clinical hyperthyroidism status at 180 days. Started Sep 2021; status: completed.

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Drugs

seleniumvitamin dmethimazole
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Conditions

Graves' diseasehyperthyroidism

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