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Ponatinib versus imatinib with reduced-intensity chemotherapy in newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia
2018-000397-30Phase 3Active
- Sponsor
- Takeda
- Start
- Aug 2018
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Phase 3, randomised, open-label trial in acute lymphoblastic leukemia (ALL) comparing Ponatinib + reduced-intensity chemotherapy with Imatinib + reduced-intensity chemotherapy (2 arms). Primary endpoint: MRD-negative complete remission. Started Aug 2018; status: active.
02
Drugs
ponatinibimatinib
03
Conditions
acute lymphoblastic leukemia (ALL)
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