Trial intelligence / Profile preview

Stage IV childhood renal tumor trial comparing upfront VAD versus VCE

2018-000533-13Phase 3Active

Sponsor
German Society for Pediatric Oncology and Hematology
Start
Jun 2018
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial of vincristine, actinomycin D, doxorubicin, carboplatin and etoposide in Nephroma and Wilms' tumor (2 arms), sponsored by German Society for Pediatric Oncology and Hematology. Primary endpoint: Overall metastatic response rate after 6 weeks of preoperative chemotherapy. Started Jun 2018; status: active.

02

Drugs

vincristineactinomycin Ddoxorubicincarboplatinetoposide
03

Conditions

NephromaWilms' tumor

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