Trial intelligence / Profile preview

QPI-1002 for Prevention of Major Adverse Kidney Events After Cardiac Surgery

2018-000757-49Phase 3Terminated

Sponsor
Quark Pharmaceuticals
Start
Aug 2018
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
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Overview

Phase 3, randomised, double-blind trial in acute kidney failure (AKF) and major adverse kidney events (MAKE) comparing QPI-1002 IV infusion with Placebo IV infusion (2 arms). Primary endpoint: Primary Efficacy Endpoint. Started Aug 2018; status: terminated.

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Drugs

teprasiran
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Conditions

acute kidney failure (AKF)major adverse kidney events (MAKE)

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