Trial intelligence / Profile preview

Asciminib plus imatinib versus continued imatinib versus switch to nilotinib in CML-CP without deep molecular response

2018-001594-24Phase 2Active

Sponsor
Novartis
Start
Jul 2018
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial of asciminib in chronic myelogenous leukemia (CML) (4 arms), sponsored by Novartis. Primary endpoint: Molecular Response (MR4.5) rate at 48 weeks. Started Jul 2018; status: active.

02

Drugs

asciminib
03

Conditions

chronic myelogenous leukemia (CML)

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