Trial intelligence / Profile preview

RAVEN: brolucizumab versus aflibercept in macular edema secondary to central retinal vein occlusion

2018-001788-21Phase 3Terminated

Sponsor
Novartis
Start
Mar 2019
Modality
Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes, Engineered Antibody Formats → Antibody-Based Therapeutics, scFv Fragments → Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
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Overview

Phase 3, randomised, double-blind trial in central retinal vein occlusion (CRVO) comparing Brolucizumab arm with Aflibercept arm (2 arms). Primary endpoint: Change from baseline in BCVA at Week 24. Started Mar 2019; status: terminated.

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Drugs

brolucizumabaflibercept
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Conditions

central retinal vein occlusion (CRVO)

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