Trial intelligence / Profile preview

ATRA plus anastrozole versus anastrozole alone in pre-operative HR-positive/HER2-negative early breast cancer

2018-001856-36Phase 2Terminated

Sponsor
Mario Negri Institute for Pharmacological Research
Start
Jun 2021
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial in breast cancer comparing ATRA plus anastrozole with Anastrozole alone (2 arms). Primary endpoint: Ki67 responder rate. Started Jun 2021; status: terminated.

02

Drugs

tretinoinanastrozole
03

Conditions

breast cancer

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