Trial intelligence / Profile preview

Atezolizumab plus neoadjuvant ddAC followed by paclitaxel, trastuzumab, and pertuzumab in early HER2-positive breast cancer

2018-001881-40Phase 3Completed

Sponsor
Roche
Start
Sep 2018
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 3, randomised, double-blind trial in breast cancer comparing Atezolizumab + ddAC-PacHP with Placebo + ddAC-PacHP (2 arms). Primary endpoints: Pathological complete response in PD-L1-positive population and Pathological complete response in ITT population. Started Sep 2018; status: completed.

02

Drugs

atezolizumab
03

Conditions

breast cancer

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