Trial intelligence / Profile preview

Phase II radiotherapy plus durvalumab without prophylactic neck irradiation in head and neck squamous cell carcinoma (N0)

2018-001976-39Phase 2Active

Sponsor
GORTEC
Start
Oct 2018
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of durvalumab in head and neck squamous cell carcinoma (HNSCC), Oral Mucosal Carcinoma, oropharyngeal squamous cell carcinoma (OPSCC) and 2 more, sponsored by GORTEC. Primary endpoint: Regional (neck) nodal control rate. Started Oct 2018; status: active.

02

Drugs

durvalumab
03

Conditions

head and neck squamous cell carcinoma (HNSCC)Oral Mucosal Carcinomaoropharyngeal squamous cell carcinoma (OPSCC)squamous cell carcinoma of the hypopharynxlaryngeal squamous cell carcinoma (LSCC)

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