Trial intelligence / Profile preview

Optimizing MATRix as remission induction in primary central nervous system lymphoma

2018-002115-96Phase 3Active

Sponsor
Klinikum Stuttgart
Start
Jan 2021
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial of rituximab, methotrexate, cytarabine, thiotepa, carmustine and 1 more in primary central nervous system lymphoma (PCNSL) and Diffuse Large B-Cell Primary Central Nervous System Lymphoma (2 arms), sponsored by Klinikum Stuttgart. Primary endpoint: Event-free survival. Started Jan 2021; status: active.

02

Drugs

rituximabmethotrexatecytarabinethiotepacarmustine
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Conditions

primary central nervous system lymphoma (PCNSL)Diffuse Large B-Cell Primary Central Nervous System Lymphoma

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