Trial intelligence / Profile preview

LOTIS-3: loncastuximab tesirine plus ibrutinib in advanced DLBCL or MCL

2018-002625-38Phase 2Completed

Sponsor
ADC Therapeutics
Start
Oct 2018
Modality
Small Molecules, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of loncastuximab tesirine and ibrutinib in diffuse large B-cell lymphoma (DLBCL) and mantle cell lymphoma (MCL), sponsored by ADC Therapeutics. Primary endpoint: Safety and tolerability (Phase 1). Started Oct 2018; status: completed.

02

Drugs

loncastuximab tesirineibrutinib
03

Conditions

diffuse large B-cell lymphoma (DLBCL)mantle cell lymphoma (MCL)

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