Trial intelligence / Profile preview

TOGO: Tocilizumab versus methylprednisolone in active moderate-severe Graves' orbitopathy

2018-002790-22Phase 2Completed

Sponsor
IRCCS Fondazione Ca’ Granda Ospedale Maggiore Policlinico
Start
Mar 2019
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, randomised, single-blind trial in Graves' ophthalmopathy (TED) comparing RoActemra arm with Solu-Medrol arm (2 arms). Primary endpoint: Proportion of patients improved at 24 weeks. Started Mar 2019; status: completed.

02

Drugs

tocilizumabmethylprednisolone sodium succinate
03

Conditions

Graves' ophthalmopathy (TED)

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